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Refetoff, Samuel
One or more keywords matched the following items that are connected to Refetoff, Samuel
Item TypeName
Concept Age Factors
Concept Growth Disorders
Concept DNA-Binding Proteins
Concept Insulin
Concept Insulin-Like Growth Factor I
Concept Growth
Concept Protein Binding
Concept Transcription Factors
Concept Insulin Resistance
Concept Thyroxine-Binding Proteins
Concept Time Factors
Concept RNA-Binding Proteins
Concept GTP-Binding Protein alpha Subunits, Gs
Concept Basic-Leucine Zipper Transcription Factors
Concept Hepatocyte Nuclear Factor 1-alpha
Concept Insulin-Like Growth Factor Binding Proteins
Concept Iron-Binding Proteins
Concept Hepatocyte Nuclear Factor 1
Concept Paired Box Transcription Factors
Concept Hypoxia-Inducible Factor 1, alpha Subunit
Concept Kruppel-Like Transcription Factors
Concept Sex Factors
Concept Growth Hormone
Concept NF-E2-Related Factor 2
Concept GTP-Binding Proteins
Concept Hepatocyte Nuclear Factor 1-beta
Concept Vascular Endothelial Growth Factor A
Concept Forkhead Transcription Factors
Concept Carrier Proteins
Academic Article The relative expression of mutant and normal thyroid hormone receptor genes in patients with generalized resistance to thyroid hormone determined by estimation of their specific messenger ribonucleic acid products.
Academic Article In vitro expression of thyroxine-binding globulin (TBG) variants. Impaired secretion of TBGPRO-227 but not TBGPRO-113.
Academic Article Multiple genetic factors in the heterogeneity of thyroid hormone resistance.
Academic Article Thyroid function tests and characterization of thyroxine-binding globulin in the carbohydrate-deficient glycoprotein syndrome type I.
Academic Article Effects of aging on glucose regulation during wakefulness and sleep.
Academic Article Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH.
Academic Article Thyroxine-binding globulin: organization of the gene and variants.
Academic Article An additional carbohydrate chain in the variant thyroxine-binding globulin-Gary (TBGAsn-96) impairs its secretion.
Academic Article Selective pituitary resistance to thyroid hormone produced by expression of a mutant thyroid hormone receptor beta gene in the pituitary gland of transgenic mice.
Academic Article Modification of thyroid hormone and 9-cis retinoic acid signaling by overexpression of their cognate receptors using adenoviral vector.
Academic Article Effect of thyroid hormone on growth. Lessons from the syndrome of resistance to thyroid hormone.
Academic Article Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone.
Academic Article Autoantibodies from patients with autoimmune thyroid disease do not interfere with the activity of the human iodide symporter gene stably transfected in CHO cells.
Academic Article Sequencing of the variant thyroxine-binding globulin (TBG)-San Diego reveals two nucleotide substitutions.
Academic Article Mutations in the sodium/iodide symporter (NIS) gene as a cause for iodide transport defects and congenital hypothyroidism.
Academic Article Identification of thyroxine-binding globulin-San Diego in a family from Houston and its characterization by in vitro expression using Xenopus oocytes.
Academic Article Failure of membrane targeting causes the functional defect of two mutant sodium iodide symporters.
Academic Article Responsiveness to thyroid hormone is enhanced in rat hepatocytes cultured as spheroids compared with that in monolayers: altered responsiveness to thyroid hormone possibly involves complex formed on thyroid hormone response elements.
Academic Article Complete thyroxine-binding globulin (TBG) deficiency produced by a mutation in acceptor splice site causing frameshift and early termination of translation (TBG-Kankakee).
Academic Article Complete thyroxine-binding globulin (TBG) deficiency in two families without mutations in coding or promoter regions of the TBG genes: in vitro demonstration of exon skipping.
Academic Article Characterization of T(4)-binding globulin cleaved by human leukocyte elastase.
Academic Article Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo.
Academic Article Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone.
Academic Article Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency.
Academic Article Low TSH requirement and goiter in transgenic mice overexpressing IGF-I and IGF-Ir receptor in the thyroid gland.
Academic Article RXR receptor agonist suppression of thyroid function: central effects in the absence of thyroid hormone receptor.
Academic Article Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep.
Academic Article Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor.
Academic Article Partial thyroxine-binding globulin (TBG) deficiency in a family with no detectable mutation of the TBG gene.
Academic Article Partial deficiency of thyroxine-binding globulin-Allentown is due to a mutation in the signal peptide.
Academic Article Analysis of the PAX8 gene in congenital hypothyroidism caused by different forms of thyroid dysgenesis in a father and daughter.
Academic Article Three novel mutations causing complete T(4)-binding globulin deficiency.
Academic Article Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice.
Academic Article Complete thyroxine-binding globulin (TBG) deficiency caused by a single nucleotide deletion in the TBG gene.
Academic Article Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo.
Academic Article Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: clinical characterization and exclusion of candidate loci.
Academic Article Mutations in SECISBP2 result in abnormal thyroid hormone metabolism.
Academic Article Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface.
Academic Article Sequencing of the variant thyroxine-binding globulin (TBG)-Quebec reveals two nucleotide substitutions.
Academic Article Replacement of Leu227 by Pro in thyroxine-binding globulin (TBG) is associated with complete TBG deficiency in three of eight families with this inherited defect.
Academic Article Molecular basis for the properties of the thyroxine-binding globulin-slow variant in American blacks.
Academic Article Triiodothyronine stimulates specifically growth hormone mRNA in rat pituitary tumor cells.
Academic Article Novel biological and clinical aspects of thyroid hormone metabolism.
Academic Article Familial juvenile autoimmune hypothyroidism, pituitary enlargement, obesity, and insulin resistance.
Academic Article Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity.
Academic Article The syndrome of inherited partial SBP2 deficiency in humans.
Academic Article Clinical and molecular characterization of a novel selenocysteine insertion sequence-binding protein 2 (SBP2) gene mutation (R128X).
Academic Article Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent.
Academic Article A new inherited abnormality of thyroxine-binding globulin (TBG-San Diego) with decreased affinity for thyroxine and triiodothyronine.
Academic Article A mutation causing reduced biological activity and stability of thyroxine-binding globulin probably as a result of abnormal glycosylation of the molecule.
Academic Article Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta.
Academic Article Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor.
Academic Article Selenium supplementation fails to correct the selenoprotein synthesis defect in subjects with SBP2 gene mutations.
Academic Article A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism.
Academic Article A single copy of the recently identified dual oxidase maturation factor (DUOXA) 1 gene produces only mild transient hypothyroidism in a patient with a novel biallelic DUOXA2 mutation and monoallelic DUOXA1 deletion.
Academic Article Inherited thyroxine-binding globulin abnormalities in man.
Academic Article Graves' disease associated with familial deficiency of thyroxine-binding globulin.
Academic Article Effect of estrogen on the synthesis and secretion of thyroxine-binding globulin by a human hepatoma cell line, Hep G2.
Academic Article Normal cellular uptake of thyroxine from serum of patients with familial dysalbuminemic hyperthyroxinemia or elevated thyroxine-binding globulin.
Academic Article Characterization of thyroxine-binding globulin secreted by a human hepatoma cell line.
Academic Article Mutations in the NKX2.5 gene and the PAX8 promoter in a girl with thyroid dysgenesis.
Academic Article Isoelectric focusing variant thyroxine-binding globulin in American blacks: increased heat lability and reduced serum concentration.
Academic Article X-chromosome-linked inheritance of the variant thyroxine-binding globulin in Australian aborigines.
Academic Article The effects of low doses of depot estradiol and testosterone in teenagers with ovarian failure and Turner's syndrome.
Academic Article The computer in the diagnosis of thyroid disease.
Academic Article Elevated serum thyroglobulin level in congenital thyroxine-binding globulin deficiency.
Academic Article Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes.
Academic Article Human thyroxine-binding globulin gene: complete sequence and transcriptional regulation.
Academic Article Variant thyroxine-binding globulin in serum of Australian aborigines: a comparison with familial TBG deficiency in Caucasians and American blacks.
Academic Article Sequence of the variant thyroxine-binding globulin of Australian aborigines. Only one of two amino acid replacements is responsible for its altered properties.
Academic Article Induction of hypothyroidism and hypoprolactinemia by growth hormone producing rat pituitary tumors.
Academic Article Mice deficient in dual oxidase maturation factors are severely hypothyroid.
Academic Article A novel thyroid hormone receptor-beta mutation that fails to bind nuclear receptor corepressor in a patient as an apparent cause of severe, predominantly pituitary resistance to thyroid hormone.
Academic Article Parameters of thyroid function in serum of 16 selected vertebrate species: a study of PBI, serum T4, free T4, and the pattern of T4 and T3 binding to serum proteins.
Academic Article T3 thyrotoxicosis. Thyrotoxicosis due to elevated serum triiodothyronine levels.
Academic Article The differential stimulatory effect of thyroid hormone on growth hormone synthesis and estrogen on prolactin synthesis due to accumulation of specific messenger ribonucleic acids.
Academic Article Suppression of serum thyrotropin (TSH) by L-dopa in chronic hypothyroidism: interrelationships in the regulation of TSH and prolactin secretion.
Academic Article Effects of 7, 12-dimethylbenz(a)anthracene and estrogen on the transplantation and growth of a rat pituitary tumor.
Academic Article Genetic polymorphism of rhesus thyroxine-binding prealbumin: evidence for tetrameric structure in primates.
Academic Article Inherited defects of thyroid hormone metabolism.
Academic Article Inherited X chromosome linked thyroxine-binding globulin (TBG) deficiency in a homozygous female.
Academic Article The role of glycosylation in the molecular conformation and secretion of thyroxine-binding globulin.
Academic Article Radioimmunoassay for serum triiodothyronine: evaluation of simple techniques to control interference from binding proteins.
Academic Article Continuing occurrence of thyroid carcinoma after irradiation to the neck in infancy and childhood.
Academic Article Hypogonadism induced by a transplantable, prolactin-producing tumor in male rats: hormonal and morphological studies.
Academic Article Nuclear triiodothyronine-binding protein: partial characterization and binding to chromatin.
Academic Article Alterations in thyroxine (T 4 ) and tri-iodothyronine (T 3 ) binding to serum proteins by heat.
Academic Article Gene screening in Japanese families with complete deficiency of thyroxine-binding globulin demonstrates that a nucleotide deletion at codon 352 may be a race specific mutation.
Academic Article Relationship of oligosaccharide modification to the cause of serum thyroxine-binding globulin excess.
Academic Article Disappearance rate of endogenous and exogenous human growth hormone in man.
Academic Article Direct application of radioiodinated aminoacyl tRNA for radiolabeling nascent proteins.
Academic Article Measurement of thyroxine uptake from serum by cultured human hepatocytes as an index of thyroid status: reduced thyroxine uptake from serum of patients with nonthyroidal illness.
Academic Article Immunoreactive growth hormone in endemic cretins in Ecuador.
Academic Article Chiari-Frommel syndrome in a patient with primary adrenocortical insufficiency.
Academic Article Estimation of the T 4 binding capacity of serum TBG and TBPA by a single T 4 load ion exchange resin method.
Academic Article Effects of "jet lag" on hormonal patterns. I. Procedures, variations in total plasma proteins, and disruption of adrenocorticotropin-cortisol periodicity.
Academic Article Endemic goiter with hypothyroidism in three generations.
Academic Article Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone.
Academic Article Familial thyroxine-binding globulin deficiency in a patient with Turner's syndrome (XO). Genetic study of a kindred.
Academic Article TBG deficiency: description of two novel mutations associated with complete TBG deficiency and review of the literature.
Academic Article Bidirectional thyroxine exchange in pregnant sheep.
Academic Article Early in vitro induction of rat pituitary GH mRNA by T31.
Academic Article Metabolism of L-thyroxine (T4) and L-triiodothyronine (T3) by human fibroblasts in tissue culture: evidence for cellular binding proteins and conversion of T4 to T3.
Academic Article Effects of "jet lag" on hormonal patterns. II. Adaptation of melatonin circadian periodicity.
Academic Article High prevalence of thyroxine-binding globulin deficiency among Bedouin infants in southern Israel.
Academic Article Common tests of thyroid function in serum.
Academic Article Nocturnal exercise phase delays circadian rhythms of melatonin and thyrotropin secretion in normal men.
Academic Article Interrelationships in the regulation of TSH and prolactin secretion in man: effects of L-dopa, TRH and thyroid hormone in various combinations.
Academic Article Thyroid hormone relationships between maternal and fetal circulations in human pregnancy at term: a study in patients with normal and abnormal thyroid function.
Academic Article Retrospective and prospective study of radiation-induced thyroid disease.
Academic Article Simultaneous translation of growth hormone and prolactin messenger RNA from rat pituitary tumor cells.
Academic Article Postirradiation screening for thyroid nodules.
Academic Article Demonstration of rapid light-induced advances and delays of the human circadian clock using hormonal phase markers.
Academic Article In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice.
Academic Article Comparison of thyroidectomized calf serum and stripped serum for the study of thyroid hormone action in human skin fibroblasts in vitro.
Academic Article Translation of prolactin and growth hormone messenger RNA from rat pituitary tumour cells. Stimulation of GH mRNA activity by triiodothyronine [proceedings].
Academic Article Multifactorial control of the 24-hour secretory profiles of pituitary hormones.
Academic Article Inherited abnormality of thyroxine-binding globulin with no demonstrable thyroxine-binding activity and high serum levels of denatured thyroxine-binding globulin.
Academic Article Variant thyroxine-binding globulin in serum of Australian aborigines: its physical, chemical and biological properties.
Academic Article Effects of "jet lag" on hormonal patterns. IV. Time shifts increase growth hormone release.
Academic Article Dopaminergic control of prolactin mRNA accumulation in the pituitary of the male rat.
Academic Article Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.
Academic Article Hypothyroidism in a Brazilian kindred due to iodide trapping defect caused by a homozygous mutation in the sodium/iodide symporter gene.
Academic Article Congenital hypothyroidism due to mutations in the sodium/iodide symporter. Identification of a nonsense mutation producing a downstream cryptic 3' splice site.
Academic Article Complete deficiency of thyroxine-binding globulin (TBG-CD Buffalo) caused by a new nonsense mutation in the thyroxine-binding globulin gene.
Academic Article Molecular cloning and primary structure of rat thyroxine-binding globulin.
Academic Article Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts.
Academic Article Differentiation of two abnormalities in thyroid peroxidase causing organification defect and goitrous hypothyroidism.
Academic Article Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidism.
Academic Article Metabolism of thyroxine-binding globulin in man. Abnormal rate of synthesis in inherited thyroxine-binding globulin deficiency and excess.
Academic Article Leukocyte alkaline phosphatase in hypothyroidism and hyperthyroidism. Response to initiation of thyroxine replacement therapy.
Academic Article Generation of functional thyroid from embryonic stem cells.
Academic Article Reduced affinity for thyroxine in two of three structural thyroxine-binding prealbumin variants associated with familial amyloidotic polyneuropathy.
Academic Article Reduced clearance rate of thyroxine-binding globulin (TBG) with increased sialylation: a mechanism for estrogen-induced elevation of serum TBG concentration.
Academic Article A study on the inheritance of thyroxine-binding globulin (TBG) deficiency from data obtained in 13 families detected by a neonatal screening program.
Academic Article Study of four new kindreds with inherited thyroxine-binding globulin abnormalities. Possible mutations of a single gene locus.
Academic Article Radioimmunoassay of anterior pituitary hormones.
Academic Article Abnormal thyroxine metabolism in hyposomatotrophic dwarfism and inhibition of responsiveness to TRH during GH therapy.
Academic Article Parameters of thyroid function in maternal and cord serum at term pregnancy.
Academic Article Radioimmunoassay detection of endorphins from long-term culture of human pituitary tumour cells.
Academic Article Growth hormone responses to thyroid hormone in the neonatal rat: resistance and anamnestic response.
Academic Article Two cases of thyroid dysgenesis caused by different novel PAX8 mutations in the DNA-binding region: in vitro studies reveal different pathogenic mechanisms.
Academic Article Familial dysalbuminemic hyperthyroxinemia in a 4-year-old girl with hyperactivity, palpitations and advanced dental age: how gold standard assays may be misleading.
Academic Article Inherited defects of thyroxine-binding proteins.
Academic Article Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice.
Academic Article Aberrant Cerebellar Development in Mice Lacking Dual Oxidase Maturation Factors.
Academic Article Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.
Academic Article A Novel Mutation (S54C) of the PAX8 Gene in a Family with Congenital Hypothyroidism and a High Proportion of Affected Individuals.
Academic Article Changes in Hepatic TRß Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.
Academic Article Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice.
Academic Article Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia.
Academic Article Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families.
Academic Article Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature.
Academic Article Novel Mutations in the NKX2.1 gene and the PAX8 gene in a Boy with Brain-Lung-Thyroid Syndrome.
Academic Article GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation.
Academic Article NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland.
Academic Article Clinical recognition and evaluation of patients with inherited serum thyroid hormone-binding protein mutations.
Academic Article Very Severe Resistance to Thyroid Hormone ß in One of Three Affected Members of a Family with a Novel Mutation in the THRB Gene.
Academic Article Increased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in Mice.
Academic Article Increased Prevalence of TG and TPO Mutations in Sudanese Children With Congenital Hypothyroidism.
Academic Article Nonautoimmune Hyperthyroidism Caused by a Somatic Mosaic GNAS Mutation Involving Part of the Thyroid Gland.
Academic Article Mice Hypomorphic for Keap1, a Negative Regulator of the Nrf2 Antioxidant Response, Show Age-Dependent Diffuse Goiter with Elevated Thyrotropin Levels.
Academic Article SWI/SNF Complex Mutations Promote Thyroid Tumor Progression and Insensitivity to Redifferentiation Therapies.
Academic Article Increased Hepatic Fat Content in Patients with Resistance to Thyroid Hormone Beta.
Academic Article Novel DIO1 Gene Mutation Acting as Phenotype Modifier for Novel Compound Heterozygous TPO Gene Mutations Causing Congenital Hypothyroidism.
Academic Article Thyroidal Transcriptomic Profiles of Pathoadaptive Responses to Congenital Hypothyroidism in XB130 Knockout Mice.
Academic Article A Novel Pathogenic Variant in PAX8 Leads to Familial Congenital Hypothyroidism.
Academic Article Foxe1 Deletion in the Adult Mouse Is Associated With Increased Thyroidal Mast Cells and Hypothyroidism.
Concept PAX8 Transcription Factor
Concept Thyroid Nuclear Factor 1
Grant THYROID PHYSIOLOGY STUDIES OF INHERITED DISORDERS
Grant STUDIES ON REGULATION AND MECHANISM OF HORMONE ACTION
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